Apple Application Support is required to run iTunes, QuickTime and other Apple installed products (do not remove this if you use any of these programs). If you remove this program you will need to reinstall it in order for iTunes to load. The program is also used to connect iTunes to the various iOS devices such as the iPhone, iPad and iPod Touch.

“Unlike traditional screen reader, VoiceOver is built into the operating system, so you can use new applications directly accessible. No need to buy an upgrade for VoiceOver, install a fresh copy and add the application to a "white list". Moreover, VoiceOver commands work the same in all applications, so when you learn to use them, you will for any accessible application.”